 Abstract background adult T-cell leukemia, lymphoma, ATLL, is a rapidly progressing type of T-cell non-Hodgkin lymphoma that is caused by the infection of human T-cell leukemia virus type 1, HTLV1. For major subtypes of ATLL exist, including acute, lymphoma, chronic, and smoldering. There are currently no reliable biomarkers for diagnosing these subtypes. To identify potential biomarkers, researchers used weighted gene co-expression network analysis to analyze the expression patterns of genes and micro-RNAs, MANAs, in ATLL samples from different subtypes. They then identified mRNA gene interactions between MANAs and target genes, which can help distinguish the different subtypes of ATLL. This study revealed several mRNA gene interactions that may serve as diagnostic biomarkers for different ATLL subtypes. We are article.tv, links in the description below.