 Chronic kidney disease, CKD, is a growing global health issue affecting both men and women. In particular, women face unique challenges related to their reproductive health, which can be exacerbated by CKD. These include irregular or absent menstrual cycles, decreased libido, increased risk of preterm labor and low birth weight babies, and vitamin D deficiency. Healthcare providers should be aware of these issues and provide appropriate counseling and support for patients with CKD. This article was authored by Murdad Zomitkesh and Mohamed Reza Tamadon.