 In 2017, the prevalence of multi-drug-resistant Klebsiella pneumoniae at Dr. Soaraji Terdinogoro Central Hospital, Clayton, Central Java was 57.28% with resistance to a wide range of antibiotics. Maripenum and amicacin were found to have the best efficacy against this strain of K. This article was authored by Handi Virawan, Titic Nuriya Studi, and Haran Erwadi.