 The study aimed to characterize hyperurusemia's relationship with metabolic syndrome in Japanese children and adolescents with obesity between 2005 and 2008. Out of 1027 participants, 213 were found to have hyperurusemia, which was significantly higher in males and older age groups. 65 out of the 213 subjects with hyperurusemia had metabolic syndrome, while only 111 out of 814 without hyperurusemia had it. The most common abnormal component of metabolic syndrome was triglyceride, followed by blood pressure and fasting blood glucose. The study suggests that hyperurusemia's association with metabolic syndrome in obese Japanese children and adolescents should receive more attention, starting from early childhood. This article was authored by Li Teng, Masaru Kubota, Iyako Nagai, and others.