 This study proposes a novel approach to constructing dendritic cell, DC, based tumor vaccines using magnetic nanoparticles. The particles are designed to actively and efficiently deliver antigens to the cytoplasm of DCs, promoting antigen cross-presentation in DC activation. This process leads to increased antibody production and improved immunological memory, which could potentially improve the efficacy of DC vaccines. This article was authored by Lei Honghuang, Zhonghua Lu, Chongjia Wu, and others.