 The Mpox virus spread rapidly in high-income countries during the first half of 2022, mainly affecting gay, bisexual and men who have sex with men, GBMSM, communities. Increased awareness and health warnings led to a decrease in the number of people becoming infected, while vaccines targeted at high-risk groups were found to be highly effective in reducing the number of new cases. By July, the virus had reached its peak, but it was predicted that this would be followed by a gradual decline as the virus lost its ability to spread quickly due to the development of immunity among GBMSM. This article was authored by Samuel P. C. Brand, Massimo Cavallaro, Fergus Cumming, and others.