 Liposomes are a promising platform for drug delivery with numerous advantages such as improved stability, enhanced bioavailability, and reduced side effects. Despite significant progress in preclinical trials, the clinical translation of liposome-assisted drug delivery systems has been slow. Current challenges include the need for further optimization of lipid formulations, the development of more efficient methods for loading drugs into liposomes, and the identification of suitable routes of administration. This article was authored by Lisa E. Circum, Tejaswi Eve Arati, Tejaswi Eve Arati, and others.