 This study examined the relationship between socioeconomic, medical, and demographic factors and working age population mortality in Russia. It found that life security and working conditions were the two most significant factors influencing mortality rates, contributing 48% and 29% respectively. Factors related to living standards and the state of the health care system accounted for only 14% and 9%. The study also identified the need to monitor the impact of socioeconomic factors on the dynamics and mortality rate of the working age population in order to improve the effectiveness of social programs. This article was authored by Mihagelo Jakovljevic, Olga Koslova, Maria Makarova, and others.