 Parkinson's disease, PD, is caused by the degeneration of certain nerve cells in the brain, leading to a range of motor and non-motor symptoms. Oxidative stress is believed to be a major contributing factor to the progression of PD, and antioxidant compounds are thought to be beneficial in reducing the damage caused by free radicals. Polyphenols, found in fruits, vegetables, and other plant sources, are powerful antioxidants that have been shown to protect against oxidative stress and slow down the progression of PD. Further research into the potential benefits of polyphenols in treating PD is warranted. This article was authored by Pooja Middle, Sunchit Danker, Samrat Chauhan, and others.