 Vascular implants are artificial conduits designed to replace diseased arteries, but their long-term success depends on their ability to mimic the mechanical and biological behavior of an artery, which requires a thorough understanding of its structure and function. Common textile manufacturing techniques are used to design vascular implants for research and commercial purposes, but matching attributes of a synthetic substitute to those of a native artery remains a challenge. The work reviewed the design aspect of textile vascular implants and compared them to the structure of a natural artery as a basis for assessing their success as an implant, with the goal of encouraging future design strategies for improving long-lasting vascular implants. This article was authored by Charanpreet Singh, Cynthia S. Wong, and Shewan Gai Wong.