 Tanchinone is a lipophilic compound derived from the roots of salvia miltyariza, which has been proven to be highly effective in combating tumors in various parts of the body. It prevents cancer cell reproduction and induces cell death by inhibiting the PI3K slash ACT signaling pathway, NFKappa B pathway, BCL2 family, caspase cascades, microRNA, MAPK signaling pathway, P21, STAT3 pathway, MIR30B, P53, PTPN11 slash SHP2 axis, beta-catenin, and SKP2. However, the properties and mechanisms of Tanchinone's antitumor effects remain unclear, and further research is needed to gain new perspectives for its development and clinical application. This article was authored by Pinyu Zhang, Wendy Lu, and Yuan Wang.