 The study develops a strategy to design and evaluate high entropy alloys, HEAs, for structural use in the transportation and energy industries, using pallets of elements chosen to meet target properties of each HEA family and methods to build HEAs from these pallets. The study shows that intermetallic phases are consistent with HEA definitions and includes both single phase, solid solution HEAs and HEAs with intentional addition of a second phase for particulate hardening. A thermodynamic estimate of the effectiveness of configurational entropy to suppress or delay compound formation is given and a three-stage approach is suggested to systematically screen and evaluate a vast number of HEAs by integrating high throughput computations and experiments. Key components such as materials libraries with microstructure gradients and high throughput tensile testing are currently missing and suggestions for future HEA efforts are given. This article was authored by Daniel B. Miracle, Jonathan D. Miller, Oleg N. Senkov and others. We're article.tv, links in the description below.