Inxi is developed to work on most GNU/Linux distributions. The script comes pre-installed in Epidemic, Linux Mint and AntiX. Arch Linux has an AUR inxi package. We hope, as more maintainers and users discover and find inxi a nice tool, it will find its place in more distributions.
Inxi works on Konversation, Xchat, irssi, Quassel, as well as on most other IRC clients. Quassel includes (usually an older version of) inxi.
See inxi options here for list of options. Always check inxi -h to get the full list of the latest options (the wiki page may become outdated).