 The Rockefeller Clinical Scholars, KL2, program has been successful in providing junior translational scientists with the necessary tools and resources to become leaders, in their field. Since its inception in 1976, 40 scholars have graduated from the program and gone on to careers in academia, government service, industry, and private medical practice. Additionally, these scholars have received numerous grants and awards, including $3 million from the National Institutes of Health, as well as foundation and philanthropic support. These scholars have also made significant contributions to the advancement of translational science, such as developing new treatments and technologies, and translating their findings into improved human health. This article was authored by Sarah J. Slesinger, Michelle Romanik, Jonathan N. Tobin, and others.