 This study examined the effects of animal assisted interventions on the quality of life, pain intensity, and state anxiety in children with rheumatic diseases and adolescence with chronic pain syndromes. The results showed that the quality of life increased significantly over time, as did state anxiety in some participants. Additionally, there was a decrease in state anxiety following the intervention, although this was not reflected in the data. Finally, no significant differences were observed between the intervention and control groups regarding pain perception, frequency, or intensity.