 Hi, I am Dr. Sachit Abraham, Consultant Dematologist at Manipal Hospital in Bangalore. Acne is a combination of many different factors. One of the main reasons for acne is having a genetic tendency to get the problem. And it also involves certain other factors which aggravate the problem, like certain drugs can aggravate the problem or certain hormonal conditions. And basically it is a multi-factorial reason. There are many different reasons. One is genetics, environmental factors, hormones, drugs, stress, all these play a role to produce acne. But basically the fundamental thing is that person should have a genetic tendency to get the problem.