 The transition from nearly zero emission building, NZB, to positive energy building, PEB, models is a new trend, driven by the need to increase efforts to address climate change targets and the ambition for a clean energy transition in the construction sector. This study focused on the functional and energy regeneration of abandoned buildings, considering that many abandoned European buildings are often located in a strategic part of the city. To what extent can these buildings be transformed into a PEB? What would be the meaning of this new association? The findings suggested that rethinking abandoned buildings as PEB could drive new trends to synchronize the socio-technical evolution of energy infrastructure and urban regeneration plans. This article was authored by Maurizio Sabilla, Duhatoubi, and Fonby and Henry Abanda.