 The patient presented with intellectual disability, microcephaly, short stature, diabetes, and spontaneous puberty delay. Genetic testing revealed a homozygous mutation in the TRNT-10A gene, leading to a diagnosis of TRNT-10A syndrome. This syndrome is characterized by intellectual disability, microcephaly, short stature, diabetes, and spontaneous puberty delay. Additionally, the patient experienced hypoglycemia followed by diabetes in late childhood, suggesting that GH deficiency and primary ovarian failure may be additional findings of this syndrome. This article was authored by Zeynep Sikler, Tuba Kahnpe, Kevin Kaulkluff, and others.