 This research program aims to develop a theoretically informed framework for AI implementation in health care, through collaboration and co-design between researchers, health care professionals, patients, and industry stakeholders. The first part of the program focuses on two specific objectives, developing a framework for AI implementation and carrying out empirical studies guided by the framework. The second part of the program addresses a third objective, which is to apply the developed framework in clinical practice to develop regional capacity for AI implementation. The project started on July 1, 2021, with Stage 1 activities, and will continue until June 30, 2026. This article was authored by Petrus Fedberg, Julie Reed, Per Nielsen, and others.