 The term is tissue agnostic. What does tissue agnostic mutation or driver mean? That means that it does not matter. The way we always look at cancer is histopathology. You take a piece of the tissue, you throw it on the slide, you stain it, and you say it looks like squamous. And that was important because for whatever reason, like an adenocarcinoma and the colon may not behave the same way as an adenocarcinoma lung. So it was very important for the tools we had, which was cytotoxic chemo. Now we're realizing, yo, it doesn't really matter what's on this slide as far as the histopathology goes. It's more because now we're at a molecular level. We're not looking at the conglomerate of cells, but inside to actually look at the pieces and all the switches, we can actually say, if we target it, it doesn't matter what it is, it can respond. If you have one or two mutations, then hopefully we will have developed a precision med that can go after the thing that's causing the cancer, block it, get a great outcome for the patient. If you have a lot of mutations, hey, immuno-oncology works well for you then.