 This article discusses the use of extracellular polymeric substances, EPS, released by microorganisms as a safe and effective method for removing heavy metal contaminants from soil and water through biosorption. EPS is composed of proteins, polysaccharides, eronic acids, humic substances, and lipids, with exopolysaccharide, EPS, being an essential component that sequesters positively charged heavy metal ions due to its net anionic makeup. The article highlights current research on the use of bacterial cells and their EPS in various forms for biode toxification and emphasizes the potential of this method for sustainable, economic, and eco-friendly remediation of heavy metal-contaminated systems. This article was authored by Pratima Gupta and Bataldi Wan.