 Centrioles are essential for the formation of cilia and flagella. They also form the core of the centrosome, which organizes microtular rays important for cell shape, polarity, motility and division. We have used super-resolution 3D structured illumination microscopy to analyze the relationship of 18-centriole and pericentriola matrix, PCM, components of human centrosomes at different cell cycle stages. This article was authored by Katarina F. Sonnen, Lothar Schemele, Heinrich Leonhart and others.