 This study found that chestnut shells can be used to produce a bioactive extract that retains more polyphenol than other methods of extraction. After in vitro digestion, the extract showed increased bioavailability and antioxidant activity, suggesting it could be used as a nutritional supplement. Additionally, the extract was able to pass through the intestine and deliver elagic acid to the bloodstream, which suggests it may have potential health benefits. This article was authored by Diana Pinto, Anna Margarita Silva, Stefano Dallaqua, and others.