 I'm not talking about paying you a compliment. I'm talking about a process, a crazy process that starts with a protein and there's actually like 25 proteins involved in this crazy cascade of chemical reactions that you do not have to know them all. The end result of the compliment cascade, the end result of the compliment cascade is something called MAC, which is a membrane attack, oh yeah, complex. That says complex because that's what the MAC attack is about. MAC, dude, this is so cool. Through the process of start here, something will initiate the compliment cascade. And if all the proteins come along through the process, you'll actually end up with this thing that all the proteins come together and form essentially, it's almost like initiating apoptosis. It creates a complex that pops the bad guy. So the membrane attack complex pops the pathogen and it's a general thing. And here's what's really interesting. If something initiates compliment, you can actually have antibodies initiate compliment. Remember what antibodies look like? And antibodies, we've seen them already when we talked about blood typing, but we're about to enter the world of holy antibody fun times with the acquired immune response. Antibodies have this little place, this little receptor zone in their armpit and that actually binds with one of the first chemicals in the compliment cascade and can initiate the cascade. So the presence of antibodies, there's lots of antibodies if you are initiating a serious immune response to a bad guy, especially after we've activated the acquired immune response, which we haven't talked about yet. Lots of antibodies mean we'll have lots of opportunities to go through this compliment cascade. Members now, the end game is this membrane attack complex, but the fact is that all these 25 intermediate chemicals along the way also have various functions. For example, some of them are inflammatory cytokines or mediators of inflammation, inflammation molecule. So they're going to initiate an inflammatory response. Others are opsonins. Oh yeah, what's that word mean? Opsonin. I honestly can't remember if I told you what this meant yet. Opsonin is any chemical that initiates phagocytosis. So this compliment cascade pops the bad guy, but along the way initiates inflammation and phagocytosis. So we're basically creating a chemical doodoo storm and we have an immune response. And even though we've separated out innate and acquired, they absolutely overlap. The next lecture, we're going to talk about the acquired immune response and highlight those places where there actually is significant overlap. But you can save that fun times for then. So goodbye now.