 Hello. I'm Jenny Monti. I'm the social media specialist for NHGRI. Perhaps more importantly, I am a referee. I'm happy to be here today on April 25th, the perfect date. It's not too hot. It's not too cold. All you need is a light jacket. I'm here to introduce the segment you've all been intrigued by on the agenda. Who is the goat? The NHGRI director goat? You're about to find out. Let's cue that competition. Just wait, Green. Just wait, man. You're going to be so sorry you took me on. He's so 90s. He's not the goat. He's so yesterday. He is so the behind of genomics, not the forefront of genomics. It's not even going to be a competition. You're going to lose this so bad. It's not a chance. I don't know. DNA Day for you is going to be such a disaster. When you're the goat, you're the goat, and I'm the goat. I'm the genome goat. I even have a G on my back, both for genome and for goat. I really told you that's what it's all about. Save this for the competition, you guys. Okay. I'll see you in the competition, Francis. Ready? Go. Remember, Francis, DNA makes RNA, not vice versa. Are you sure you are going to get mixed up and try to do translation? Because I've heard you screw that up before. You know, there's a lot of intricacy here. My version is going to have enhancers in it, and I bet yours won't. Because you're probably still in the prokaryotic phase of understanding this. Who do you call prokaryotic? Just don't have to see how it turns out. And then we can decide whether you're still doing the lack operon or something a little fancier. I'm not lacking for an operon, but I am absolutely able to bring in more transcription factors than you do because I know how to get more shapes. I'm grabbing these off the internet, and this is actually structurally good. I know the A word, animation. All about the animation. You're just such a showman. And by the way, it would help if you used a PowerPoint version, other than from like the 90s or something. Let's find out what he's doing. I think I got the wrong end of this. That's a distraction. You're supposed to be working on your PowerPoint. I got it. That's what the genomes are. We're going to get anything with that stupid long camera. No, you're just making this up. You're calling that a camera? It's all about the film. That's pathetic. Now, what do you look at? Okay, I'm going to get what you're getting so much better. The only animal I've seen is him. This is just ridiculous. Eric, you never should have agreed to this part of the competition. Clearly, you're going to get smoked. And remember, Francis, they need to be in focus. Oh, I got that. No, you may be focusing, but the camera's not. Oh, well, I'm in control here. Yeah, I got it. I nailed it. The samples of corrected DNA origami first wins. Ready? It looks very competent there. You did that all wrong. I think your result is going to be chromothripsis. Chromothripsis. Look it up. It's a great word for people to know. And now, after seeing what you've done, they'll know why it is so important. Okay, I think I'm way ahead of you here. Look at that. I didn't see your diet. Look at that. Yeah, you did that way too fast. There's no way that could... Let's get in there. It's getting close. And done. Done. Check this out. Isn't that beautiful? Perfect right-handed double healer. All right, Francis. I admit you won this one. Oh, boy. I don't think that flew very well. And it's kind of a big deal, because it's the 20th anniversary of the completion of the human genome project. Literal decades. The final round. Allow me to reintroduce our contenders. In this corner, coming down the stairs, Francis Collins, standing tall at nearly 10 feet, weighing his 3.3 grams, which is strangely the same weight as a butterfly, brings his A-game today, with a height of 5 feet 10 inches. Approximately the same size as a kangaroo, weighing in at 40 and 200 pounds. It's might, not height. Yeah, it is both of those, actually, so you're in trouble. You didn't wear your green scarf. And did you ride out here on your moped today? No, no, no, no, no. I got here by alternate transportation today. I'm ready. All right. Now, hang on a moment. I just want to be sure that that statement you just made is absolutely verifiable, because don't you work for him? No, she works for her. She works for me. She works for him? Yeah. So I feel vulnerable here. It's called a power imbalance. Can I have reassurance? Is there like somebody's going to certify here that this is all completely unknown? You don't trust her? I'm a professional wreck. And her face is totally trustable. The rest of her is not, but her face is totally trustable. All right, I'm going to assume honesty here. As you both, as you simply try to get a sympathy vote from the audience that somehow this is rigged. You didn't tell me there were weasels in the box. Live weasel. Live weasel. We got to wrestle a weasel? I can't draw. Did you pick genome editing on this easel? Can it be words? Can it be pictures? It could be whatever it is for three minutes. But I don't want him to see mine. You think I would copy you? Is that what you're worried about? You're afraid I'd laugh. Genome editing. You have three minutes. What was the O part? How come he has two colors? And I get one. I get green. That's fine. But he should not have two magic markers. All right, which one do you want? Remember the deal we cut when you told me this three days in advance what it was? You said I would have three markers. Aha. You want red or black? Drop a marker, Collins. Drop it. Okay. I'm done. How much time now? Eric is in record time. This is accessible. We have one clock. One minute left. He's going fancy. I'm going simple. I would have figured that. Focus is important. This is how you make progress in science. You have a task. You get the right people to work on it with you, not like a loner over there trying to do it all himself. You figure out how to make amazing things happen, like changing just one left of the DNA code. There you go. Right there. Okay. You didn't have any artwork here at all. Cool magic. Is that how you think science works? It's like all cool magic. It's simple. And this is CRISPR. Describe what you have drawn. I've described when you have the wrong sequence and then you do some magic. You just offended everybody here who has genetic variance that they have a wrong sequence. Did you know the LC program has said a lot about that? It just isn't right. That's not helping. It's a variation, Eric. It's a variation. But then you're being judgmental if you then call it right. Well, I have prime editing because I'm in my prime. Sounds like Amazon. This is the kind of editing where you can change any base pair. In this case, a G gets edited to a C. And this is all done by amazing combination of molecular biology and chemistry. So I've got to give credit to David Lu, who's the guy who really made this work in a much more optimal way for practically any base pair. So credit is important. There you have it, prime editing. I'm dead. Who wants simple? Just because he drives a Harley. For me because this is my current boss, but I think the... Actually, not anymore. Good thing I've taken up a second career as a wreck. All right. Payments later. Oh, I didn't say that. It's not metal. I'm sorry. That looks like a recycled award from our award ceremony. How could that happen around here? Oh, no. You would never do that? Well, I'm... Wow. All right. I will wear it with pride, even if it is recycled. The goat. I think that was bad. I think we get off stage. Congratulations. Francis didn't even have the guts to wear the shorts.