 Human Immunodeficiency Syndrome, HIV, is a major public health concern worldwide, especially in developing countries like Pakistan. This study evaluated the pregnancy outcomes of HIV-positive mothers in Pakistan. It was observed that most of the women were multiparous and had a high rate of unsterilized nasal or ear piercings, as well as a history of blood transfusions and dental procedures in unsterile environments. Additionally, 22% of the spouses were also HIV-positive. The study showed that HIV-positive mothers are more likely to experience spontaneous abortion, intrauterine death of fetuses, preterm deliveries, and deaths due to advanced stages of the disease. These findings highlight the need for improved prevention strategies and better access to care for HIV-positive mothers in Pakistan. This article was authored by Shahidah Hussein Tehrir, Muhammad Afzal, Hamna Atta, and others.