 Genome-wide association studies have identified several genes associated with type 2 diabetes, T2D. However, these studies have largely focused on populations of European descent, leaving many other populations underrepresented. This study aimed to identify genetic risk factors for T2D in a Pakistani population. The study utilized whole-exam sequencing, WES, to identify potential risk alleles, followed by mass array genotyping to confirm the results. The study found four genes associated with T2D, PARG, HNF4A, GLS3, MTNR1B, IRS2, NOCH2, NOCH2, and NOCH2. These findings provide valuable insight into the genetics of T2D in a Pakistani population and may help inform future research efforts. This article was authored by Asif Jan, Zakhiela, Sajid Ali, and others.