 This study examined the characteristics, management and outcomes of patients with traumatic brain injury, TBI, and associated risk factors. The results showed that the majority of patients were male, aged between 16 and 30 years old, and had a mean age of 30.9 years. Additionally, the study found that CNS infections were common among these patients, with 56.7% developing such infections. Furthermore, the study also revealed that a significant association existed between CNS infections and certain risk factors, including age, presence of CSF leak at presentation, type of surgery, and duration of emergency room, ER, stay. In addition, the study found that mortality was significantly higher in patients with low GCS scores, CSF leaks, intraventricular hemorrhages, TBI types, polytrauma, and CNS infections. Overall, this study highlights the importance of strict infection control and prevention measures to reduce the incidence of CNS infections and improve patient outcomes. This article was authored by Archie Naz, Gulam Rashid, Mirza Shazadbeg, and others. We are article.tv, links in the description below.