 This study investigates the antibacterial and antibiofilm properties of four lactobacillus strains, lactoplantobacillus plantarum, lactobacillus acidophilus, lactobacillus johnsoniii, and lactobacillus dolbuachii, against two pseudomonas aeroginosa strains. The study found that the four lactobacillus strains had varying degrees of antibacterial activity, with L. Plantarum having the highest antibacterial activity. Additionally, the study found that the four lactobacilli strains had varying levels of antibiofilm activity, with L. Plantarum having the most effective antibiofilm activity. Overall, these findings suggest that the four lactobacilli strains have potential applications in the prevention and treatment of pseudomonas aeroginosa infections. This article was authored by Mariana Martins-Drewmond, Mariana Martins-Drewmond, Ana Paula Tappiacosta, and others.