 Since the emergence of the first cases in Wuhan, China, the novel coronavirus, 2019 in Cov, infection has rapidly spread to other provinces and neighboring countries. Estimating the basic reproduction number using mathematical modeling can help determine the potential and severity of an outbreak, as well as provide critical information for identifying the type of disease interventions and intensity. A deterministic compartmental model was developed based on the clinical progression of the disease, epidemiological status of the individuals, and intervention measures. The estimated values from likelihood and model analysis suggest that the control reproduction number could be as high as 6.47, 95% CI 5.71 to 7.23. Sensitivity analyses showed that intensive contact tracing followed by quarantine and isolation, or travel restrictions, can significantly reduce the control reproduction number and transmission risk. Increasing quarantine by 100,000 baseline value would have similar effects to travel restrictions. It is important to assess how expensive, resource-intensive measures implemented by the Chinese government can contribute to the prevention and control of the 2019 NCO. This article was authored by Biao Tang, Xiao Wang, Chen Li, and others. We are article.tv, links in the description below.