 The study found that the majority of patients admitted to the Cole Hospital in the Democratic Republic of the Congo with suspected monkeypox virus infection had positive test results for the virus. The most common symptoms included fever, rash, malaise, sore throat, and lymphadenopathy. The most common physical exam finding was a monkeypox rash. Patients under 5 years old had the highest number of lesions. Patients with hypoalbuminemia had a higher risk of developing severe disease. Patients with fatal disease had higher maximum geometric mean values for viral DNA in their blood, maximum lesion count, and day of admission mean levels of alanine aminotransferase and aspartate aminotransferase. This article was authored by Philip R. Pittman, James W. Martin, Placid Mbola Kingabini, and others.