 The study found that estrogen can reduce the effects of susplatin on kidneys. This is due to its ability to decrease levels of creatinine and blood urea nitrogen, which are indicators of kidney function. Additionally, estrogen can reduce oxidative stress caused by susplatin through its ability to increase levels of nitric oxide and decrease levels of malondialdehyde. This article was authored by Elisa Hedi, Medinemapax, Merium Moini, and others.