 This study investigates the safety and tolerability of consuming bovine milk oligosaccharide, BMO, supplements in healthy adults, and their effect on fecal microbiota and microbial metabolism. The study found that BMO supplementation was well tolerated and had no significant impact on store consistency or fecal microbiota composition. Additionally, it showed that BMO supplementation could shift fecal microbiota towards beneficial strains, which may have implications for symbiotic treatments with probiotics that selectively metabolize oligosaccharides. This article was authored by Jennifer T. Smilowitz, Danielle G. LeMay, Karen M. Calanetra, and others.