 Good morning everybody and welcome to TCGA's third annual symposium. I can tell everyone's excited to get going because it's the first time I've been in a scientific meeting and everybody is actually seated in their seats at the starting time, which is pretty remarkable. And I think it's a real testament to the kind of success that we've all had in TCGA, which is really thanks to, first of all, the leadership from the program staff at the NCI and the NHGRI who've really been, I think, doing remarkable public service over the last years. I think it's second due to the scientific network that we're part of and third due to our huge network of physician collaborators throughout the world and all of those patients who've consented to have their specimens shared for this study. And I think we've seen some really great steps forward in this year as well. The JC has told me that the 10,000th sample has shipped to all of the centers in the last shipment from the BCR. And in addition, we've got a number of marker papers that are moving forward. The long adenocarcinoma and the gastric adenocarcinoma papers are both impressed at nature, as we speak. And the thyroid carcinoma and kidney chromophobe cancer papers are under review. And I think they'll soon be followed by the low-grade glioma and melanoma papers. So it's been a year of extraordinary progress. And I'm just going to turn it over to co-chair Marco Mara for some remarks. Thank you very much, Matthew. And I won't go on. I'll just add my welcome and thanks to those of Matthews. I think the only comment that I really want to make is one also in thanks to those with the vision to have promoted the whole initiative so long ago. I think the marker papers are truly a testament to the power of the resource. But I think we're only starting to exploit it. And so I look for many more great things to come on into the future. Thank you. So with no further ado, we'd like to welcome our keynote speaker, Bob Grossman, as agreed to join us from the University of Chicago, where he's a computer scientist working in the Department of Medicine. And he's also a leader of the Open Cloud Consortium. And Bob, thank you very much for joining us this morning.