 The study uses Monte Carlo simulations to investigate the effect of reversible sacrificial binding sites on the mechanical properties of single linear polymer chains based on load-bearing metalloproteins found in muscle biceps, revealing that the topology of the bonds determines the position and spacing of sacrificial force peaks, while the height of these peaks is dependent on effective chain length. This article was authored by S. Soren Nabavi, Matthew J. Harrington, Oscar Paris, and others.