 The researchers have identified several biomarkers associated with diabetic kidney disease, DKD, as well as regulators and drugs that may help treat it. They found that certain immune-related genes are overexpressed in patients with DKD, while other genes are under-expressed. Additionally, they discovered that certain proteins and signalling pathways are altered in these patients, which can lead to further deterioration of kidney function. Furthermore, they identified several micro-ionase and transcription factors that may serve as potential therapeutic targets for treating DKD. Finally, they also found that certain drugs can modulate the expression of these genes and proteins, suggesting that these drugs may be useful in treating DKD. This article was authored by Shengnan Chen, Boli, Lei Chen, and others.