 Butine, a natural compound derived from the root bark of Butia superba, has been shown to be effective against melanoma in both in vitro and in vivo studies. It inhibits the growth and migration of melanoma cells, as well as reducing the production of fegf, which is associated with angiogenesis and metastasis. This suggests that butine may be useful for treating melanoma. This article was authored by Yue Lai, Xiwei Wang, Chen Hinchang, and others.