 Assisted reproductive technologies, arts, are crucial in animal production, genetic resource preservation, and genetically modified animal generation, especially in small laboratory species like mice. The Reichen Bioresource Research Center, BRC, maintains over 9,500 strains of mice with diverse genetic backgrounds and has developed art specific to each strain's reproductive and physiological characteristics, including superovulation, IVF, cryopreservation, transportation, and ET. Superovulation using anti-enhyben serum combined with estrous synchronization has increased production efficiency by threefold in the C57BL-6J strain. The BRC also successfully developed arts for over 50 wild-derived strains, which have been cryopreserved for future use. Improving and developing arts for mice and other small laboratory species will enhance the cost-effectiveness of routine operations at repository centers and provide high-quality animals for research purposes. This article was authored by KG Machide. We are article.tv, links in the description below.