In the film the EPA wants to shut down the laser containment unit because it is in violation of an EPA code. The Ghostbusters try to tell them it is a bad idea but they do not listen. When it is shut down all of the ghosts escape into the city and everyone is worse off. When Walter Peck sees the results he blames the Ghostbusters and asks that the cops arrest them.
As you can see from the comments the scene is a sort of Rorschach Test for whatever ill happens be occurring in large or small parts of society at any given the moment.