 Hi everyone, I am Dr. Kumar Dev Arvind Rajamanya, consultant orthopedic surgeon, Manipal Hospital in Spikefield. The knee joint is one of the most largest and complex joints in our body, which bears 1.5 times a body weight during walking, 3 times a body weight during climbing, and 5 times a body weight during squatting. It's quite natural that the knee joint is subjected to such heavy stresses during our lifespan. Osteoarthritis or degenerative disease of the knee is of two types. 1. Primary, which is mainly age-related wear and tear. 2. Secondary, mainly inflammatory or post-traumatic. Symptoms of osteoarthritis are pain, swelling, stiffness and deformity. Depending upon the grade of the osteoarthritis, patients usually find it difficult to do most of their activities of daily living, such as walking, climbing, or getting up from a seated posture. Osteoarthritis can be classified into four grades radiologically, i.e. with the help of AX-ray, and the treatment modalities are followed accordingly. Lifestyle changes are of paramount importance in the management of osteoarthritis, and these include weight loss and maintaining adequate BMI, healthy eating habits, regular exercises, and avoiding activities which cause repeated strain to the knee, such as squatting, sitting cross-leg, and stair-climbing. Physiotherapy can be machine modalities which help relieve the acute pain, and stretching and strengthening exercises of the muscles around the knee which help in stabilizing the knee joint. Knee braces can range from simple knee caps to hinge knee braces to complex off-loading braces depending upon the severity of the osteoarthritis. Medications can be oral anti-inflammatories, analgesics or topical applications of the same. Glucose amines are believed to slow down cartilage damage. Visco supplementation with hyaluronic acid helps in lubrication of the knee joint. Quarticosteroids are extremely helpful in inflammatory arthritis or in osteoarthritis with acute knee pain. Surgical options include arthroscopy, where the damaged structures are diborided which may alleviate the symptoms. Osteotomies or realignment surgeries which offload the weight from the affected compartment of the knee, and in the last stages a total knee replacement. In a total knee replacement, the damaged cartilage and its underlying bone are replaced with artificial metal which are called as prosthesis with highly cross-linked polyethylene into meaning there. The goals of a total knee replacement are achieving perfect alignment, soft tissue balancing and deformity corrections, and stable painless mobility which invariably reduces the pain and improves the functional quality of life. These are just an overview of the various treatment options available to manage osteoarthritis of the knee and the effectiveness of each modality depends upon the severity or the grade of osteoarthritis for that particular patient. Patients with mild to moderate symptoms can opt for video consultations through our Manipal Hospital website. The ones with the severe complaints should consider visiting the doctor to initiate appropriate treatment protocol.