 Autophagy is a process whereby cells degrade and recycle their own components to maintain homeostasis. In this study, researchers investigated how glial cells use autophagy to remove debris from damaged neurons. They found that a specific subset of autophagy-related genes are necessary for glial cells to efficiently clear away debris from damaged neurons. These genes encode proteins involved in the conjugation of lipids to the protein LC3, which is essential for the formation of autophagic vesicles. The researchers also discovered that these genes are important for the survival of animals following traumatic brain injuries. This study provides insight into how glial cells can be used to promote the recovery of the injured nervous system. This article was authored by Aaron Sobo, Vorek Vinks, Eshwaya Sanjay Chatra and others.