 The study investigates the biological roles and mechanism of CERC, CERC-1 in regulating inflammation in RAFLSMH7A cell line, showing that overexpression of CERC, CERC-1 inhibits proliferation, induces apoptosis, reduces inflammatory cytokines, increases antioxidant enzymes and NRF2 expression, and promotes CERC-1 signal pathways through MIOLU-132. This article was authored by Suhua Zhong, Zhang Zhao, and Wu Chongma.