 This research aimed to develop silver nanoparticles, AGNPs, using various plant extracts for antibacterial applications. The papaya seed extract was found to be the most effective in synthesizing AGNPs, while the n-hexane fraction was the only one that successfully produced them. Characterization techniques revealed that the AGNPs were marked at 430 nanometers with UVVIS spectroscopy and 1640 CM1 with Fourier Transform Infrared Spectroscopy, FTIR. Scanning electron microscopy, SEM, showed that they had a spherical shape with an average diameter of 91.3 nanometers. Particle size analysis, PSA, confirmed their nanoscale dimensions. All fractions contained alkaloid compounds and the ethyl acetate fraction also contained compounds with specific wave numbers at 2623 CM1, 1737 CM1, and 1237 CM1, corresponding to NH, C equals O, and CN, respectively. All fractions at different concentrations, 25%, 50%, 75%, 10%. This article was authored by Hedyon Idradi-Surura, Harris Abdullah, Sana Ferdinand Jinting, and others. We are article.tv, links in the description below.