 This study examined the effectiveness of anti-neRNA for treating triple negative breast cancer using RNA nanoparticles targeting stem cell markers. Two studies were included in the analysis, which showed that the average hydrodynamic diameter of 3WJ slash CD133-APT slash ANTAC mere 21 nanoparticles was 10.30 nanometers, with a standard deviation of 7.10 nanometers. Additionally, Zeta potential was found to be minus 25.19 MV. Based on these results, it appears that this type of nanoparticle may be effective for treating triple negative breast cancer. This article was authored by Mariam Fathi, Sida Salmaz Riazzi, and Nassim Pordamgan.