 The study examined the effect of maternal high fat diet, HFD, consumption during pregnancy and lactation on exercise performance and energy metabolism in male mouse offspring. It found that MHFD consumption resulted in decreased exercise performance and training efficiency in the offspring. This could be due to insufficient muscle energy supply during prolonged exercise training. Additionally, this compromised exercise performance may increase the risk of obesity development in adulthood. This article was offered by Isabel Walter and Suzanne Klaus.