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Nerintuki alphabetia tisha tis dima, maen o'i an equilibrium Introduct Maen Quasta Life iini caim Japanese Maen Quasta Life Japanese English English English English English English English English English English English English English English English English English Rai, rai, rai, rai, rai, rai, rai. Rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, rai, r awi pleitau me感au maera me rangemba mei luiu. Apu aia rai cyntatao apagau rai. Ako unufnain, aotei rai beti cenua. Aau maera maera aotei rai beti cenua, aotei rai beti cenua, aotei rai beti cenua. Aotei pa kura nua sylpa kuwis. Apu aia rai beti c perché rai beti cickau kaipainu. Pasha sepira wazau mei luua anata eitri. Pasha sape甚麼? Aotei unufnaine wazau aotei, naau, maere grei gandiau. So, I know what she's going to talk about should be interesting. It's very timely for me to talk. Well, sleep day? Yeah, so do rooms as you have will affect your sleep. So, to relatively recently to obesity is really in terms of diet that we really think about when we think of tackling. That sleep has come into the picture and you see as one of the behaviours to look in the new Canadian physical activity guidelines also part of life. There was a relationship between 1992 since that time there have been a national in the main but also here that actually time at night you do have things like diet and physical activity. Two fold higher if you're a short is what is short and what is long and every individual says that odds have been obese additional hour of sleep a night. We think of longitudinal studies we generally think of one really longitudinal studies. So what they did was actually looked at the stage that they had multiple measures of this. When they did that they found that the difference in the whole BMI unit and the long lasting effect particularly when there was a NMI really focused on the quantity of sleep and that makes sense you can have a real sleep or 8 hours or whatever. So there is some national data of a student into four groups early to bed and so on and you can see there that children who had a late bedtime duration and the differences in demographics that existed is that believe it or not parents out has gone to bed but they don't necessarily know how to live with the advent of the tablets and the smartphones speak from much experience and they give us an objective way of actually measuring sleep so for watch you can wear them on the wrist the orange non-worn when a child goes to sleep because of the large margin around that. So what we've done recently is this is from a couple in Auckland and Dunedin, very high proportion all we were trying to look at is what's more different measures of sleep quality really important when it comes to sleep so even stint bedtime and so on you first go to sleep at night and sleep so you want a high sleep efficiency or a longitudinal data longitudinal data, we had sleep and for seven days at a time we had dietary information to control for and what we show is associated with BMI, later BMI sleep in the baseline and year six and year two but bedtime so later bedtime increases the risk so at least at that level of day important the good news is we can Louise has already talked about we had the woman and hopefully their partners we then went into the homes when the infants were three pappins and about letting the infant learn the rates of obesity and that did not the rates of obesity were in the non-sleep we also released a similar study showing that in there and one of their main messages for instance the first protocol so try some other prevalence of overweight at one year of age Louise's talk is that we've also measured because three and a half from five years of age and at three and a half there so there was some sort of system and by the five years of age P equals 054 for those who are interested very importantly and very interestingly what we can intervention that these kids were sectional nutrition and activity intervention at five years of age so real food for thoughts that leave us under behaviour we've tackled is it a behaviour parents a lot of for many many years over nutrient and there's a lot of resistance and difficult some ways perhaps a more attract sorry that's obviously conversion there between Mac and PC Louise was talking about and the local say that some of us did make a difference on BMI there is a talking about however when it came none of those studies influence physical activity did one or two out of ten variables on the other hand we do seem to be able to make an impact a way in two parents intensive interventions Poi was incredibly raff it was a long lasting effect and what about TAG work out at birth that predicts the risk in parents it's a first child the risk of childhood obesity is actually less than 1% that to a beast parents lock during pregnancy and that risk goes up to 70 interventions we need to work out let me know the mechanisms there's a bit of literature but on the food side of the energy balance equation more time to go to the fridge but there are maybe something tied up with the act we need more sleep messages it's not something we've constant sleep messages keep a regular electronic media from the bedroom that's possibly the biggest ensure regularity so council and just the last one for any mums out there hi we have time for one or two questions sorry the question was about worldwide in the last few years so there's a lot of interest in the last 56 relatively crude data though but all age groups but there's also an interesting about the problems of sleeplessness from the business easy enough to do in a home visiting type content difficult but the messages are quite simple but you know why public health promotion there's no real groups attacking sleep and sort of any of these behaviours that needs to be done from all those different ages a module that could fit into well-child care so just to give very much to Rachel so I'd welcome Wayne Cuttional Science Challenge who's going to talk about another cut of the gut microbiome and childhood obesity in the next fifth up of a new frontier biome or gut ban while it might be new to us it's gastroenteritis with the yellow soup it might be sipped or savoured now really in a new frontier of health research which is our gut my obesity and a bit on diabetes risk other areas such as gut health so the impact or the effect of the gut from the publications you can see growing topical area many of you have weighed yourself in the last week you're actually two kilos lighter than the scales to your gut bugs so take two kilos sorry, there are 30 trillion human cells it's a large number of gut bugs we've got bugs and that consists of and okay now 12 gut bugs were commensal and quite happily but they didn't actually have any of you a different paradigm and that is we have a mutualistic effect to them and to us in terms they can actually have an adverse free back heat in St. Louis and others from mice is that mice are coprophagic of gut bugs in this interesting first study from you can see that no bacteria in their guts and they're not exposed to the GF and then he looked at to germ free mice that were colonised just for the last two weeks you can see that and that includes if he did them all fat and they didn't eat more higher so it a pet storage and just to very quickly the gut bugs were influenced self through a bunch of we've learnt a lot of other things from ice if we look at our gut microbiome of course just over half of our gut microbiome is influenced by diet nothing quite like nuking the gut microbiome then and transiently the positivity can alter the gut microbiome which is a constant part of the gut microbiome now if we look within my own our gut bugs is heaven here which is a filer of a healthy bacteria whereas the baddies with a fence to lead to increased adiposity there's a different paradigm now and bad bacteria or filer is going to be healthy a rainforest is going to be much more resilient it will cope with more environmental that has been shown in this study compare bacterial diversity or high bacterial diversity though to be slimmer for diabetes had better lipids rather than pick on achieving greater early life is associated with risk reflects breastfeeding and the same time recently from sero by the end of child microbiome is stable from 3 to 4 throughout life and then as we get older a really busy slide the sensation of dozens and dozens and does teria work the first thing to point out to scavenge an extra 1 to 200 calories of a time that's an appreciable increased calorie with whoever obese or have the diet of a short chain fatty acids and this insulin sensitivity in muscle increased inflammatory and also an effect in the brain by the effect of gut bugs on it isn't just shoveling more calories into you it's doing as I've mentioned that it has an impact now there are association studies so now I'm going to move away association studies in humans and particularly children in New Zealand have a higher cesarean section common event and this section is this is a very in which they looked at children today's study an appropriate acronym for this talk and they looked at those in this but there was a 25 who were exposed to cesarean of course if you think about cesarean section or if you think potentially of the gut microbiome PH of the stomach given and colonised after that time of course the PH the stomach can make safely you know 25% in fact they obesity at all and childhood to be obese so if you look 5% risk of obesity could be obese due to cesarean section now say could another and these studies haven't been replicated again this is a large recent study the first year of life and the second year is what a number of studies have found that in the first year of life and the second year of life haven't found the same observation which children are vulnerable now intentionally given to children to see if they become obese is the question about the liberal antibiotic resistance I think we do antibiotic exposure in which children may be given the third group that I wanted to introduce you to children are born prematurely and we've conducted a number of study childhood they're insulin resistant adults born prematurely to show they're even more insulin resistant and prematurely in the mid 40s have an extra so if you think about the early life life for their gut function so they tend to be fed by mature children they have a lot of so there are lots of reasons why they've got so when we looked at these children latent for everything activity that if their gut bacteria were different that and of course that's a cross-sectional study have led to long-term changes within our GI training as well and we found so there could be different activity of bacteria because some of them can be co-accent and some of them go for activity they're going pre-term in the group or in the glutamine and thymine metabolism lower glutamate levels have been associated now so I've talked to you about the role of gut bacteria so are there intervention studies that humans you can influence health and for cell infection that's a horrible form of treated with vancomycin with variable success now in this study and there was that if you basically put clean up the stall take the bacteria a very high rate of cure for how consider to be one of the one of the now I've talked to you about mouse to mouse transfer so this and this BMI so a fat twin and a thin twin humus mice and they found that they got fatter and then when they the fat bacteria with a mouse who had thin similarly if we look at the mouse gut bacteria they got thinner these changes were more exaggerated in an unhealthy human it's getting closer and it was in cross-clostridium difficile infection alive she developed cross-clostridium difficile after transfer this woman so it's the reverse of what we're talking about fact that there may be a role here up to diabetes and again all of these are very diabetes put a nasogastric tube down those with type 2 diabetes and found that percent 6 weeks after transplant on your weight my mum is on us and there is a general consensus that is see how effective they are could this be a meaningful for me so what we're about to technique where we can extract the gut capsule kind of like handmade chocolate that and we've shown good diversity in bacteria that bit so that bit we've got anchors teenagers with samples from very T and it's going to answer the question you transfer bacteria can that lead to appreciable weight loss I'm not sure see that in him so in the interest of I think like to have a reasonable stab as it's half comes from the best of new castles we see him frequently at the obesity meetings in Asia and it's really been doing so thank you very much just sort of inconsistence because even if it might not necessarily be good for your health and when you're comfortable you can sit back down so I'm getting young people moving moving more often taking research from the lab in a lab setting and moving it into schools of level with more more individuals but the way that young people spend their time is a concern across the globe is in the way that our people do that Lancet Group published a series of papers and but how active should young people be is the guideline for young people and there's a green base recreation in Australia we also have ensuring that young people engage in activity in the presentation I think it's the second now and a grade of 62% of females now what was interesting about that group because when you looked at how active data of 15 to 18 year olds were just for comparative purposes we've also gone through the same process for the last in comparison anyway we were awarded a D minus I'm really interested in adolescence is that physical activity declines dramatically during adolescence and this is a problem for all manner of rural and community based interventions so there's a small number of interventions that are targeting we did a recent meta-analysis looking at it as Rachel had mentioned previously only meta-analysis affects size of 0.24 a difference of 2 minutes a day which is certainly not much we see in physical activity during adolescence where people see challenges and we promote physical activity what is the evidence around promoting activity about sedentary behaviour I'm really going to be talking about recreation but specifically it really makes you huff and puff and puts you right out of breath being described as the new smoking doesn't matter if you meet the physical activity then you're risk of health but I thought I'd just throw out a recent data from over a million men and women and the authors conclude 60-75 minutes now 2 minutes is actually twice the activity recommendations for adult increased risk of death associated with high sitting as confirmed as perhaps one such group we set out to try and add in young people and how that measured sedentary behaviour out there that actually have really high quality sittings it was about and the basic conclusion of the review in sedentary behaviour and cardiac metabolic health so it's certainly up in the air that the studies of interventions to reduce sedentary behaviour effect was on BMI activity but by comparison there's almost no effect BMI studies of interventions reducing sitting time the few studies that have been now conducted with quite adjustable desks in the reductions in sitting time and increases in sit to stand trans or blood pressure for the target of intervention it certainly is because obviously there's very little or no evidence that reduced adiposity in adolescence that's my take on the intensity spectrum when walking is an excellent demonstrated quite clearly that when we get people to increase and various other health outcomes increasing walking in adolescence a recent walking in adolescence and children they only found three all of these studies were short term all of them in increasing physical activity in those pop outage use increase their activity so there is some measurement issues at compounding that one of those interventions seem to have any effect and not to say that walking isn't important but the evidence doesn't support that so much for increasing walking is active transportation active transportation in young people and the ship was weak at best when we talk about resistance training we're talking about conditioning that invents loads and training modalities barbells and dumbbells but probably more in my plastic resistance the evidence in terms of the effects of resistance training in young people works it probably underestimate because we're probably going to see improvements in muscle mass the effects of resistance training on insulin adults so it's certainly a method of training where the resistance training is safe in young people to have injuries in fact the injury hours of supervised resistance training which is actually a bit of power lifting and particularly good activity for overweight adolescent easier to complete than to reason it tends to be very rewarding that being most part misunderstood by people a traditional resistance training in a study conducted by Amanda Benson usually free weight exercises plus maybe two sets of each exercise for being conducted with small samples but general they all body composition improvements and insulin resistance level the challenges are that most school things that again have an impact across a broad and a large number of you have an approach that can be done in levels so this is a study we did previously previous intervention we looked at the idea if we could train teachers to obesity prevention now it was about improving so we trained up about 30 teachers across to deliver these programs now in a gym environment we looked at a more variety approach using predominantly resistive work out to engage students in high intensity fitness infusion which is where you actually the idea behind this was really about in an environment that was enjoyable now BMI at 6 and then 12 month we did see in the top yellow on BMI I agree so these are students who are arguing that in obesity prevention we're most likely to and we'd like to see an effect on before is resistance training is safe particularly in overweight and obese adolescents now we're getting to the far end it really has incredibly reviews have demonstrated this in a cross section of findings 7 minutes of vigorous physical activity per weight in obesity and 64% vigorous activity small amounts of this hit training provide this is getting a lot of attention across the globe at the place that the idea that strong effect on their health outcomes it's typically involves short type activity or at the lower end of that now today most of the hit style training have in very controlled settings but there's certainly a laboratory setting university of technology they've been doing hit training in obese we just published a review just of hit training on BMI and but what was standing the limitations that to date most of the risk about 8-10 weeks and in small sample that setting certainly a form of training that made up we need to boost people's positive feelings about gainful is unlikely to do this if we tried to do this maximal school setting with adolescents that have tried to compare people continuous training versus hit training tend to show a training that's because hit training is fit getting up to that maximal heart rate happens from a public health perspective this is an area that really hasn't we try to hit study embedding it we're delivering three hit sessions per week for we had a control group as well the aerobic might be some jumping and some running combining some resistance based exercise with the aerobic coal just a difference between groups over time within a waste of conference and also another school based study is that they used a slightly different but instead of doing more gym based they used a basketball boxing dance football and ageing young people and this is an approach that we are they reported really large difference between groups over time vigorous activity is potent and are the effects going to be incredible over time my last area of activity and that important part of New Zealand fabric as it is a lot of outcomes it's not just about you conducted by a lead basically concluded that an adiposity was weak at best is that a lot of a lot of games around waiting for a turn they're active they're doing what they need to do analyse how much activity happens in a train it can actually be very small often as little as 20% of the time standing around listening for instructions during that time again it's about a 35 now there's lots of reasons for the study looking at a drop out the sport stops being fun for a lot of girls that wanting to focus on studying and grades become to my point about hit training and I'm sure you can all remember a bad fifth hard to see examples of experience reaching that they've received at various times video cost the intensity spectrum information away that session is just as important for obesity as well late last year we published the delivery of organised physical activity sessions language the teacher or coach uses it refers to how much time the students actually are they waiting around are they waiting for a turn many theories of behaviour change demonstrate and some volition within they do fair everyone has the opportunity to enjoy environment is a variety and making sure that people are doing things I take on five is about the deliver looked so my final thoughts shifting influences from the family to the so what we really want young people to do the direction and the activities that they're choosing to exercise where we could really have forcing young people to do some of the exercise in active mind that at such approach we'd only push the problem further down the track want young people to have the opportunities in the home and in the school environment to develop the knowledge motivation comfort and these are the things that we want young people to have to take into the futures again but thank you for listening thanks very much can I take one of the last regulation is there an enacting to their body to then where you should eat what your body says opposite way around I think as human beings we are and because from an evolutionary perspective they have to create environments where the opportunity is the easy one to believe that we do need that socio-ecological because it isn't enough the opportunity has to be there but we also have to do it so I don't think we could I was intrigued with the different when the jumping jacks and all those sorts of things but is that a case or not? I think now the way that we is essential so the larger group the NHMSE funding to do that and we're working with dance instructors and all of these sessions Martin Gabala has probably in one minute you can get phenomenal our lessons aren't going to do that so we've got to find some balance but the variety is essential has to be enjoyable and I realise this is not the main purpose of your talk but it's a physical activity because I mean it's very tempting for governments, not activity because nobody objects to how many of those people who took part because lots of people yeah no a good point and some of these things I think when I started off working in physical I don't want to know more but I haven't in some of the soft drink and some key dietary behaviours food frequency questionnaires in the past difficult type detecting any change that's not to say that some changes in diet but to answer your question I think there are some dietary changes that are going on as well wonderful talk let me take you away from imposing in the media school physical as is the four or six weeks of training prior to that time and as you indicate I have been in that lesson so I suspect that falls away more coming back to the point transiently because then they leave school and trying to get into their heads of kids by looking at more clusters of them yeah I think that's a great one of the things that's very autonomy as we put within the safe feeling like you have a sense of choice over what they just do this this is what you're doing what probably the approach is that I was saying what do you want to do in the middle so I do this with my own children would you guys like to go to if I said would you like to do a walk so choice within framework and these studies most of the studies that I will read I am involved in community based approval and if you move that we've made the parents aren't motivated by preventing health and the well-being and the academic influence parents so clearly that's an important more about doing well at school so most of this is school based to parents to support as well yeah so the work Phil Morgan as well it's called Daddy this was actually one with dads and daughters exercise on BMI was very much around age girls and again there's dads of primary school daughters are various more active and if you can get on this one because it's just been submitted to pediatrics but that is if you can get fathers to well-being and their activity levels so yeah there's we've had a fascinating first session this morning I think you'll see you back for the next session and about Professor Louise Signal who's got today to talk to you about our work on CWIS it's part of the diet program who you'll hear from later this morning so from Ireland it's HR we were very lucky because well the children live in and findings findings around the abetogenic we were lucky enough to be 12 year olds from Wellington war and automated camera and a GPS device their parents their family participating in this research it is a great pleasure they're on there and they took a photo every single front of the child of 136 where you had a wonderful work it was able to help us stratify our scientific status so we have pretty pen in the study Loam Boys and Girls which I have to say wonderful team of people and we got 2.9 GPS points are now linked to the photo the environment they create well this is the work to get photographs that show their lives what have they watched? McDonald's they have a wonderful Ph.D. cupboards and what people have hearing mark and for about one thing and couldn't hear see that they've brought any of the food there close by and from school typical shop drinks energy drinks if you are working with a task at the moment you wouldn't have is it talking about to cut the off-ball that I think we should on here what we see here might be more my work basically like what do they think about they tried to work with food marketing children we want food should be marketed it shouldn't stuff like that said if you were food marketing to children somebody said make it true boards and big sign in terms of health marketing environment child rights our research food policies healthy food administrative and real junk food relation sport sponsorship predecessor think actually we should learn making the marketing the kids removing some we could do city environment the big city in our sugary drinks price a whole where we should endanger major some of these gear hard would tax anyway we should so are convinced but Robert next associate control right space sense of urgency I agree research on that I'd also go for some of that Louise who's Collisa to morning me here today really national science project that are in a right start off about and this is a is moving on phone date appropriate also higher for Pacific probably on social use Facebook burning you can see that to use people all that came out of communities now the small scientist solutions public gets easy to tease themselves works for them and so bring the community their views have two views because unless he thinks we live in an eye it's very and so I wonder involved in answers universities partners these are some really great and she's now doing related research team time really is and the whole which is running spent a lot of research they were able to ideas really got to know trying to hear what need so that coming up ideas and protein forth process come up with a run test we have been seen they have the same tools community that come on in our sorts of stations well for my recognising that we found fell out of our consultation with the whaka well-being important from a geek these models sort of told us that connection and spiritual they lived whoops generations important connect achieving constraints well when we went back to how might it do some of the things like prototype some sort of twitter design and these are just such team that process actually works says right now right there lovely folly that we're here at the questions Mark there are so much quality to pretend focus particularly this project because there's rooms head in the backs of our mind but space mon is likely to be they're doing with their family enable them to a different physical activity things like that for integrating relevant work to also bringing in those activities happy to talk to professor to all of you in the iron and the obesity some of the motion and some of those guidance national guidance there are some opportunities there's a lot of now guidelines which are obesity here in New Zealand policy document all of us multiple demand is also needed by industry or government sectors policy documentation and actions in the other kinds of individual behaviour given that the in the recommended area all five are recommended the market or front of package around healthy food a child at a blue now an increase increment risk prevent and see for sector some of the talk a little bit more a child to see recommended of the common healthy foods standard what are the differences you'll have noticed in our recently which is great of the other time industry government there's no but I would hope for DH and by the focus of the debate documents been implemented and the British Medical tax follow that up so we're I guess ideas as you can see what is considered the recommended is not sufficient with something like and they use to fund that these benefit some work New Zealand category that's a substantial amount rating system the purpose better informed encouraging products and the UK not conducted a few years ago is that more than the use preferable didn't matter rating no system is not going level particularly mode formulation of the impact in New Zealand under embargo positive in depth but I think it will be a very limited network of policies been developed as a fantasy in place where they may not exactly but actually is to note is a very science from it impact might take policy encouraged or things occurs rare so policy impact or effective layer of the importance begins with better genes I think that I take this the change agent thank you very much the strengths of these wide range is general cost a lot of influence they are terminal and they are obviously is main kind of risk so suffrage is divided again but more with repeat from that much to our three it's been a really good lunch session opened and now colleagues on the Tone Action Network is a narration to you for the next six months don't you some of you will be saying we're on this type of research I'm just supporting that link the first one go and have a chat and with the spot page thank you we have and at the symposiums but reducing right to see the very important making on anyone wants to question that many prevent consequences as well as having I haven't had a chance to go to the University of South type to indigenous people you just come under us it's a great plenty fighting all of the say sorry Australian ending member approach will bring you you know as and it's large and assign those most vulnerable indigenous to many of you I haven't 50 for our age of death who are fortunate lies for our community, mortality burden that accounts for the communities disease lens inferences in single left for a third left most we want to get on top is a pretty and what are we facing and all of it to sort of inform Australians of it's like these mortality is expected to what this is but not a lot on a couple of we know we are seeing in our community in a fair adulthood people who think we can't grow up what do we know about Asians and the communities in care to look and as people descriptive prevalence figures that do exist in population well we do see differences smaller differences in prevalence rates to mainstream populations where mortality burden bites hardest between our people indigenous peoples and the rest of mainstream is here whether you look at the look at the area this is for average 500 50% but we are an in-state community who wants a disease of any wide despair disease across communities features through our policy they are all sick well into the policy framework we don't know we know the prevalence rate over the age of 50 communities although we know that a drive-in hospitality across all ages is that it consists of potent women in a potent driver so they strongly but we do know how to die why these women we community communities the gender, life or instable birth communities as a provider lies metro or sequenced Aboriginal people have to dislocations from 85% consequence of eyes where fine disease we do have a blindness really is the worst part hard story communities what a wish we are to access the food that we to rejuvenate in enormous food basket the taste of if you look here this is dust but always this is look at some dollars from the north to the south to the south so when communities you are going to get for the less amount of money to talk about coloniser that's it changed our the change in which was always brought through the Aboriginal very disparate and conflict diseases misticated populated land and the first through the process congregant activity ever before but the stuff we used to access was sitting down processing kilometres but our cold impacts on these always indigenous heard us as a bunch of people in a room other people were transmission one group a strap of group as and as a commission from an end life at the same time to get through and I said really quite as because so as I know not with poor poor have to tell Zara's indigenous daily base dindo into there was no and the people we asked the impact in the final depressed for what they did to their community that censor to be depraved out importantly the Aboriginal chicken we're talking about if you're done not going to sell increasingly on some really layer and gone to much significantly young age the rates that you had tied to candidates born to the really importantly about the children's mentions well this is a very concerned idea the national is indigenous to be heard these matters but we received our framework that black that was good for them actually defined who could see Aboriginal and other communities we have low table and we have skinny these are better tables dissing and that needs to the complex producing the impact or it is in our strength the final two which waters with one exception everyone what do we focus on in primary to talk to them and see if you want them to jinx if you want them to start and we thought an abro of input about no brains standable of quite care who are very good our own community disciplinary care she needs very good mechanisms we expected to get a great to Australia where to for dies contracts on to whether or not we did it's pretty energy guys and say diabetes and call potential service delivery plans prevention and monitoring that's on for the next community but that doesn't necessary points as people indigenous people about our well better future determine understand communities some better study of type 2 screen and phenotype whose we can hide intervention and my receipt if there's changes individuals project here they're not helping us build so we're trying to story is pressure money and support acts what we have work life is to come about slide or aboriginal but this is a real health drug it is here for us the way your kid needs to have you go on this or but because our children have diabetes and huck us on intervention we can sisters too important you're always only have to listen actually we're doing it and people always say we have we have actually please to repeat the question was when you might appropriate small indigent on many days clearly the reality we do know that's on our community reversion was associated the challenges have but we are trying to advise them and I think the question is from people it's being in a buy a minute proportionate and should make is every people on the ground if it does or does and gives doesn't know what it is diet thank you huck aboriginal people too quick indigent think well activity in aboriginal from national sorts range of cult people are in that trend. Men in particular, relatively physically are, become much more ting enviromentis, see a more isolated problem style behaviours. Does it exist? Communities are obsessed in seaboard, regional side. Poverty matter if you're an aboriginal person. You still may have travelling inequalities, graphical. I still can afford to down in terms of the which to make sure some of the two minutes late so. I've been asked years there, the answer is to be learned because we may be different. Yeah, so the between. How to diabetes and what lessons. Psychosocial racism rates among mortality difference people in Mexico and in remote Australia is a profile. Factor back considered some high rates in remote or maybe it's the informant. I think the more social fact circumstances are friends they live in, they're healthy. Why is it just a whole bunch of when all that's where, generating? Your speaker, Tony Maraman, I bet he's beside it not. Elec, but you never I'm a Highlander fan. I'll bellae give a gene 1-0. Reloaders, tweens and drivers of dogs, children six growing up underneath your left and just put throughout the one thirdly. Thirdly. Why? I think they both. But that, you know, my wife illustrates the contact called high reason why these from their parent 20% are unnazits, not end of London. And that's because of pitching the reasons why so are important average, okay? A BD2 doesn't modulate. We know that 80% where it's died when you work it out, God, it can die as a God. I mean, aside from monitoring single genes that can be the constant 18 year um a car when throughout your genetics that's a large piece. Explaining the variation fine. And there's three in here. I seem to have the contribution common of course. And it's really down to the common up to this. And it's because they're common the people are common. You might associate here frequency more and over the past and the people causes of either FTO, that obesity is various and I let 100 deities. These rare use in 1990 where this child didn't produce any appetite. And as the same in this case, there's been 20 to 20 years so this would be the always hung of negative obesity. The same lines has and Dr. 2015 to the four left and G that's in irregularly strongest genetic biology background. I would never feel easy to keep eating to what we can in the facts where you have risks on the society and in the environment because it increases millions of years. Eating is autonomous but drive selective as selective for other many mil interaction that may divide exposed alcohol and then in a very whole of this to combine this right here it's protective, other predicted exposure becoming more to the FTO strong interact. The context of trying to get you here make the brilliant up by a thousand this morning is the intervention and you can at variant now would we in the risk group protect my last session this would be all binary tax for exact approaches take home slide so condition health priorities medical approach standard understanding the other time health science if you de-stick it's all about poor but I had a cool and policy initiative there. Tempting to questions for Rinky Murphy. I'll be focusing on they might play a distribution I'd like to all heard and important those we've hung a a lot of the nation very unknown by Hormones illness we can't would not drip to a calorie have our cytology a step and very varied various types of food Hormones are induces Hormones are satisfied with dieting. Tempting to increase that of Drake senator released we all know this are not the multiple times effective is 20 regular types. Hormones group is receptivity injection coming up there are more more important just there is a number and things like disin to write more more more more i Planau meiriai plantarei pardopamon. Padaiki reportu ma causiepni. A는데요. A antarata goo lidle Aelin A i ui Padaiki Padaiki A Mau Kewpura Ngati, oo, pwata â maiyet'ant paiaida ni? Welsh achy in palmad, gandaersia. So mae m congresso thanai Ctrl, exoneto entitia eitheta, sépunikia gamota a poca panip즈 tidior na freshmania. Yad ja dim, bobadonngombanda eo i kiadı i ni om Express Unwan ar dar new anagata. Spuhu bai k談it yng heati. Charad Meat Hurddand Rebu Hefmut Ek akau kesadaw nidat ? Persi Mennum nidat Reba Kuura Aaminos roles of the question … Question,果n o做usblowing endeат Diabeti I'm pretty diabetes, dylan, these people have their done general life. But what's that mean of VMJ me ar, what is the beat we here in New Zealand? Is it a male remaint of a Beast's Edge so it's a NRE ups high-cap? Hopefully we'll have a bit there. You don't know what false horatities and the patient overwei tells all his down, doing some exercises New Zealand friends to go and check out dylan. Again, if we look at our guide, we'll look at 20% advice, main, it's telling me. In terms of oil on the West, ones in India get very good cl— and this will be lifestyles than on solid advice. When it's for a creation in a clinic, there is weight loss. Grad students, so when it comes with apples. And so this packet went through each of those at the— and so therapy, dietician, so ADPs published process opponents of that. And this was at the twa— there is, which is 3.7. Those from around the world was about— so there is the best effect of pragmatic, wide variation of diseases. And so we need these from the longer term, and the important that you translate. And just out of curiosity, I thought all the jury's not pragmatic into very research. We really need these to care anyway. There's some position to— and they can have this. It might not be the best one. So we're keen to get how much I see for research. I'm a patient care nurse. I'm going to try and programme work at the sessions. We've talked about— I need to work to really just need who is our leader, some evidence on this. And then we— Thank you, Kirsten. Fiona. Whether it's a referral— some of the work we have to be really— and again, they've published— I was up in the participant, and I'd see who are doing— you're learning more, students. She's going to present us underneath in a moment. We'll let you know after that. Thank you, both already. We'll take— I've seen them receive that they— wait, it's possible that she raises it. It allows— I'd like to— raises with that. Alcohol and tobacco. I should say, but I didn't answer that, because it's— I'm not sure there's no majority. Anything from— That's— I'm concluded it was to make that— Definitely on her— Thanks, Tony. Thank you all very much. Reconvene that— of her ETS. Perhaps what, where the— perhaps isn't going to dramatic them, but barrier privilege will better him. We've made her work terribly much of New Zealand. I immediately flogged for me down there, and he's also been very— Rachel. Thank you for giving me that. In the morning break, in the gut, really focus on what a new tree fulfills, which you know why. Clearly its 20s are higher. A flung, another disease, but also we know that an increase will have the beast's time. The life by the time pregnancy is one of the beast's statistics. It's sad. I don't hold of this by beasties. We're not going to stop thinking, what is this disease? So costa need to die. We go hand in, obviously, but it's conditioned so deeply, because we're day at us. And now it's really simple. Just eat and pull, and we're doing so. What's the problem with which others be eaten? Make sure the section of the company act as best as possible. That makes its regulate 20 years. My dear, it's purely against what we eat. So the gut to your brain, as soon as you own all, just eat and pack out when... Puttai, it really trick-surgers your gut part of the reason it. Known as Missy 1990, the gut about it, is we PYW up and come down beaten, beaten from all sorts of lots. And that's peanut. Well, the action, or placebo crossover, people win. All this decrease in normal way will increase the make for 20. The amazing thing that we face, that once you're on a bunch of PY signal, as much as you have, is actually... Now, the way that we can find a date represented by scans that are in the plane, is YY goes on to the person's... If we then YY, YY and the set of animals, and at the Moor disk, to see the VNP. One of the questions decreasing is the hyper-search. If we do something, the fusion, they didn't. We did see them. The anger gut binding areas in your makes for YY were actually going E, sort of saying largely reason. Look at how much they hated, how much they how hungry they predicted how much the scanner. Act on your act, moor manges as PYB, articulate blood on P1, LP1, of its license in the UK on Pluton, is slightly chronic condition in treat, but it just shows psychological look about and basic hepatitis. It's actually... doesn't work in a... interesting by an ASR in shown to have the salgarellin pro-dibe has the opposite. What's going on? Again, there are these two the entire cell desert. Not only does the system, and so does OFAR-rellin is a live early for integrated seeing act on your patch to produce oculate gut hormones. The study was quite so you said to me, and for the people who really like the fruit meal gut hormone, what protein PYS, high ASS and less fat gut hormone carb PYYS as size students X resistance as size so they were asking on what happen who are the day they're fast hunger, a day and then now we'd lead to end sort of end for the ending at the end goes to size causing the high in exercise PYYS is a much size all day. Positive effects is the same with sight done though yet or with any of you've heard I'm going to talk a little bit about FTI of the tendency to eat you dense for the last three years if you've already eaten at the chill weight gain in appetite the fortunes but I'm not well full so it is a normal weight they match them perfectly on their body we simply to their gut and we also either way and what we at risk hosted their hunger much more quickly so the amount of calories doesn't go down if we the people with the food attractive for millennia between FTIs so the ends of the finding is at risk and you're showing them PYYS when you even though they've all the air the FTIs have that telling you don't try and stay away from having no pre-exercise ex-exercise study, ex-exercise them so this is all the same that we ate is a good thing to be able to have given ex-exercise appetite intake then the AA exercise after our garellins our garellins are the most incio of the sort of potato state of the atzing one now ex-exercise so you really should be doing mechanism and they have some garellins about the biologisation the garellins things are stuck in these vicious lines of weight loss so that loss may for them sit all back on when they look to the thing that we know whose weight ever we do in an intervention it doesn't matter gradually that the weight back on am I a full chance 5% child would you try dead was shown a diet but then you put so this is be hosted 10 week period on that you actually we look at the hunger hormone going to tumings up it's the lower zoology it on the girl congratulating the energy and the end how then if size 3 is to put the stretchy biying and try one of the really if been normal to surgery fundamental quatchity in the first place this is the Swedish of really his best he would put weight on what we know on the remating and only surgery this is which involves through the rest of these two patient or two days later risk surgery patient I man 50 been told he is kindly going to John before 8 no medic anymore no treatment calculated in the blood improves improve the thing that we're 10 years undertaker you'll see the 2000 operation have got a percent getting but unfortunately control really possible medical sleep here is the 3 BMI with biplane C any so again showing you but dying to people with an HBA 50s and for the most common which is which if you're actually the other thing that so for a progression to show you the complicated follow-up and efficiency require like commendations I ever thought you'd have an electric 35 99 world wide for the case an option what we know is that this sounding calls restrict as it works so that I've just told TX then we'll handle certain so that's involved in resnetics we take them by evasion from this surgery where we look at their apological drives so what about and we've known that are more evident if we do so don't be showing that you have amount of gull as part of it so it changes your off there is a surgery out all this is a tall body weight or a response to surgery weight loss in their gull surgery don't blame us the weight loss map longer turns your type so react so on the profile light as much weight of a terastog like acting 4000 gene people before and yes we guess a common long which is to try to reach and reach these for probably 5 years so servicing to treat a bit in the my take home most to our the under health benefit where weight and the poor are a disease to act in terms of the chronic ill power to see if they by evasion feel that it's so they often need more barrier and that to do as well so that we acknowledgements and I'm sorry I've got power hard treatments and the gut one burning so that like your statement within the UK everybody wants so it's to give us some last year within the UK really stuck but I think that I think you should also learning for you can then use everybody can't have anything to I should introduce her I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I