 The topic of my presentation is MRI evaluation of spectrum of transverse myelitis. Introduction transverse myelitis is a acute inflammatory disease of spinal cord characterized by rapid onset of bilateral neurological symptoms. The symptoms can be motor in the form of symmetric or asymmetric upper or lower limb weakness depending upon the level of cord involvement, sensory disturbances in the form of hypoesthesia, spenesthesia, or allodynia, autonomic dysfunction, involving bowel, bladder, or sexual dysfunction. Symptoms evolve over hours or days, maximum clinical severity within 10 days of onset. Even though clinical features are helpful to orient the diagnostic suspicions, for example timing and severity of myelopathy symptoms, the differential diagnosis of inflammatory myelopathies is often challenging due to overlapping features. Moreover, non-inflammatory etiologies can sometimes mimic an inflammatory process in this setting. Magnetic resonance imaging that is MRI is becoming a fundamental tool for the characterization of spinal cord damage. Causes of transverse myelitis are diverse, broadly classified as etiopathic, which is a diagnosis of exclusion, and those which are attributable to underlying disease process. Transverse myelitis can be longitudinally extensive, involving more than three segments and all or most of the cross-section of the cord, or it can be short segment cord involvement, which has less than two segments of eccentric or asymmetric cord involvement. Inflammatory myelopathies can be recognized in numerous immune-mediated disorders, including multiple sclerosis, apropylene-4, IgG-positive, and MO spectrum disorder, and myelin oligodendrocyte glycoprotein, antibody-associated disease. Based on underlying pathophysiology, inflammatory myelopathies can be classified into cell-mediated autoimmune disorders that are confined to CNS, for example MS, or associated with specific antibodies primarily targeting CNS antigens, or associated with systemic autoimmune disorders having secondary CNS involvement. For example, in SLE, chockdown syndrome, and sarcoidosis. The characterization of spinal cord lesions in terms of longitudinal extension, location of axial plane, involvement of white matter, and or gray matter, specific patterns of contrast enhancement, often allows proper differentiation of these diseases. Besides imaging, paraclinical testing helps in diagnostic framing of these disorders. For example, the presence of oligolucleinol bands in CSF, and typical brain lesions involving periventricular or just acortical areas, suggest multiple sclerosis as the most likely disease cause. While autoindie bodies targeting apropylene-4 and MOG are the most frequent causes of antibody-associated transverse myelitis. AIM and methodology. AIM of study is MRI evaluation of spectrum of transverse myelitis. Methodology of the study was conducted in department of radio diagnosis, common medical college. The study included 30 patients suspected of transverse myelitis fulfilling the inclusion criteria. The standard of our protocols, that is, sahaj and axial T1, T2 images, followed by both contrast T1 images. Diffusion weighted abs sequences were taken wherever required. Inclusion criteria, those patients who were suspected of transverse myelitis based on symptoms. Such as acute or subacute onset of motor, sensory or autonomic dysfunction involving spanning cord. Patients, those who were referred for MRI evaluation as suspected transverse myelitis. Exclusion criteria, those patients were excluded who had an altered native diagnosis of cord pathology at the time of presentation. For example, traumatic cord injury, and patients who had passes of hypersensitivity to have a contrast. This is the case of 54-year-old woman with weakness in bilateral lower limbs with associated minimally retention. See, MRI numbers spying. D2 sahaj image shows mild expansion of conus with altered signal intensity in distal cord and conus. On post contrast imaging, there is thin smooth peripheral enhancement of the cord. This is another case of a 40-year-old woman presenting with sudden onset of weakness of bilateral upper and lower limbs. On T2 sahaj images, there is long segment hyperimdensity and on axial images, there is more than two-third construction of cord in movement. This is sahaj in axial post contrast image of the same patient showing faint patchy peripheral enhancement. This is MRI of a 14-year-old patient presenting with history of fever followed by all four limb weakness. Third images show long segment linear hyperimdensity involving lower cervical upper dorsal cord. On axial T2 images, central involvement of cord is noted with characteristic edge sign of grave involvement. Results of 50 patients in our study, 21 had transverse malitis as the cause for these symptoms. But as nine patients had other causes like spying cord infarction, nutritional deficiencies in the form of B2L and copper deficiencies, foundiotic myelopathies, spinal dural edu fistula and spinal metastasis. Out of 21 patients who had transverse malitis as the cause for their symptoms, 13 were females and 8 were males. 9 out of 21 patients presented with acute onset motor and sensory symptoms both. 5 patients presented with bilateral upper limb weakness only. 3 patients presented with bilateral lower limb weakness only. 2 patients presented with bowel and bladder involvement and 2 patients presented with all of these symptoms. Out of 21 patients, 10 patients were diagnosed with multiple sclerosis. That is about 47% of the total patients. 6 patients were found positive for aproposin-4 antibody disease and 4 patients were found positive for malif, oligodendrocyte, therapeutic protein, antibody. 1 patient was diagnosed with saccharinopathy. Most common MRA finding was altered cord signal intensity that is T2-stir hyper intense cord signal that was found in all the 21 patients with associated cord expansion in 14 and cord enhancement on post-contrast images in the rest 15 patients. On X-ray T2 images, most common location of the legion was peripheral that is in 11 patients forming 52 posterior patients followed by central gray and white meta-involvement in 6 and only central gray meta-involvement in the rest 4 patients. The short segment cord involvement was found in around 11 patients with the rest 10 showing long segment cord involvement, cervical dorsal spine being the most commonly involved part of spine followed by whole spinal cord involvement in only dorsal cord involvement in 4 patients while involvement of conus was found in 3 patients. For discussion, most common cause of transverse myelitis in our study was found out to be multiple sclerosis forming about 47.6% of the patients followed by neuro myelitis optical spectrum disorder and malin oligodendrocyte glycoprotein antibody disease. Most common symptom was acute onset motor and sensory weakness combined in about 42% patients followed by volatile lower limb weakness. Most common MRA finding was T2 hyper intense signal intensity of the cord followed by cord enhancement. These were my references. Thank you.