 Although there's a growing list of Alzheimer's disease susceptibility genes, even if you put them all together, they account for less than half of all Alzheimer's cases. The single most compelling piece of data on the potential control we have over the disease is the fact that if you have identical twins with the exact same genes, even if one gets Alzheimer's, the other usually does not. So we have to think about all the other contributing factors beyond just genetics. In my video on pesticides and cancer, I talked about this study. There's a list of chlorinated pesticides, including DDE, metabolite of DDT, that are classified by the EPA as probable human carcinogens. But in the study, blood levels of DDE and others were associated not with increased cancer mortality, but increased risk of other cause mortality. This led researchers to speculate it may be due to an associated increased risk of diabetes or dementia. I've talked previously about the diabetes link. What about dementia? Elevated serum pesticide levels and risk for Alzheimer's disease. A research team at Rutgers found significantly higher blood levels of DDE and Alzheimer's disease patients compared to controls. An autopsy study showed blood levels are a good proxy for brain levels. Those with the highest levels were about four times the odds of being demented with Alzheimer's. And in a Petrie, this DDE increases amyloid precursor protein levels in human brain cells, providing a potential mechanism. Here are the levels of the sticky protein implicated in the development of Alzheimer's disease before and after some DDE is added. At the levels, one finds circulating in highly exposed individuals in the general population. Put all these studies together, and there does indeed seem to be a link, consistent with data showing about a doubling of risk for developing dementia among those acutely pesticide poisoned. Among U.S. elders, DDT and its breakdown product DDE are also associated with increased risk of cognitive decline in general. DDT was extensively used in the United States from the 1940s to the 1960s. At its peak, we were churning out 180 million pounds a year, and it's still in our bodies to this day. Contaminating the bloodstreams of more than 90% of Americans and DDE, the pesticide link to quadrupling the odds of Alzheimer's, were at the highest levels. It's still in our bodies because it's still in the food supply. In my last video on the topic, I noted that the levels of DDT, DDE, and other banned pesticides and pollutants were much lower in the breast milk from a vegetarian mother, compared to breast milk of a non-vegetarian sister, and the largest difference was noted for DDE, which was four times lower in the vegetarian sister. This is what you see across the board for these kinds of pollutants. Food samples were collected from supermarkets across the U.S. Here's what they found for dioxins and PCBs and beef, chicken, pork, processed meat, eggs, fish, all plant foods put together, and dairy products. These toxins build up the food chain, so it makes sense that the most contaminated foods are meat, fish, and dairy products. 5 to 10 times higher levels in meat, eggs, fish, and dairy than what we find in plant foods. And unfortunately, cooking doesn't destroy pollutants like DDE. In fact, it may make them even more concentrated. And this is for a pesticide that may increase the risk of Alzheimer's disease as much as if you carried the so-called Alzheimer's gene, ApoE4.