 The study determined the total phenolic content, TPC, and antioxidant activity of methanol extracts of three Horitium species using various methods, including DPPH, FRAP, and ABTS. H-coroloids had the highest TPC and antioxidant activity values, while H-Americanum had considerably lower values than H-coroloids and H-Arenaceous. A high correlation was found between TPC and ABTS plus, DPPH, and FRAP. Horitium SPP, especially H-coroloids and some of H-Arenaceous isolates, may be promising natural sources of antioxidants for the food and pharmaceutical industry. This article was authored by Funda Attila.