 Chronic kidney disease, CKD, is associated with an increased risk of cardiovascular disease, CVD. This is due to several factors including traditional risk factors like age, hypertension, dyslipidemia, diabetes, and obesity, as well as non-traditional risk factors such as anemia, hyperhomocyste anemia, calcium and phosphate metabolism, vascular stiffness due to endothelial dysfunction, ED, oxidative injury, and inflammation. These factors contribute to the increased atherogenicity of CKD patients leading to higher rates of CVD. Further research is needed to better understand the underlying mechanisms of CVD in CKD patients so that new treatments can be developed to reduce the risk of CVD in this population. This article was authored by Erina Harshani Silva, Chandama Madhu Wikramatalik, Sarath Lekham Wasam, and others.